If the tracer is metabolised a series of measurements can be made and assuming exponential decline first order kinetics the volume of distribution can be determined by extrapolation back to zero time. Schoeller da van santen e peterson dw dietz w jaspan j klein pd. My source for most of this information has been the kerry brandis anaesthetic viva book. Extracellular fluid volume measurement. Duke renal physiology 23817 views. Previous electrical impedance studies that predict body fluid volume and body fat used a single measurement site between the wrist and ankle calculations based on an electrical model of the thorax suggest that with a single wrist to ankle measurement only the electrical characteristics of the legs and arms will contribute significantly to a prediction of the total body fluid volume.
The plasma volume is calculated by evans blue technique the proportion of plasma and hematocrit is by centrifugation. Am j clin nutr 1980 33122686 2693. Volume measurement of compartments. Total body water measurement in humans with 18o and 2h labeled water. If plasma is x and its volume in body is y then plasmahematocrit100 the volume in body is v. Then make proportion calculation.
Not interfere with body fluid distribution if the tracer is excreted in the urine then the loss can be determined and corrections made in the calculation. Body fluid compartments overview. The formula for calculating synovial fluid joint volume in the lavaged joints regardless of effusion is a modification of the albumin dilution method 2 which uses the measurement of a native molecule before and after dilution with a known amount of saline. Previous electrical impedance studies that predict body fluid volume and body fat used a single measurement site between the wrist and ankle calculations based on an electrical model of the thorax suggest that with a single wrist to ankle measurement only the electrical characteristics of the legs and arms will contribute significantly to a prediction of the total body fluid volume. 20150921 fluid compartments regulation of ecf volume fluid replacement. Everyone should have one.